diff --git a/library/psa_crypto_slot_management.c b/library/psa_crypto_slot_management.c
index a5c43b1b2..a18350ee1 100644
--- a/library/psa_crypto_slot_management.c
+++ b/library/psa_crypto_slot_management.c
@@ -479,7 +479,8 @@ psa_status_t psa_validate_key_persistence( psa_key_lifetime_t lifetime )
 
 psa_status_t psa_open_key( mbedtls_svc_key_id_t key, psa_key_handle_t *handle )
 {
-#if defined(MBEDTLS_PSA_CRYPTO_STORAGE_C)
+#if defined(MBEDTLS_PSA_CRYPTO_STORAGE_C) || \
+    defined(MBEDTLS_PSA_CRYPTO_BUILTIN_KEYS)
     psa_status_t status;
     psa_key_slot_t *slot;
 
@@ -497,11 +498,11 @@ psa_status_t psa_open_key( mbedtls_svc_key_id_t key, psa_key_handle_t *handle )
 
     return( psa_unlock_key_slot( slot ) );
 
-#else /* defined(MBEDTLS_PSA_CRYPTO_STORAGE_C) */
+#else /* MBEDTLS_PSA_CRYPTO_STORAGE_C || MBEDTLS_PSA_CRYPTO_BUILTIN_KEYS */
     (void) key;
     *handle = PSA_KEY_HANDLE_INIT;
     return( PSA_ERROR_NOT_SUPPORTED );
-#endif /* !defined(MBEDTLS_PSA_CRYPTO_STORAGE_C) */
+#endif /* MBEDTLS_PSA_CRYPTO_STORAGE_C || MBEDTLS_PSA_CRYPTO_BUILTIN_KEYS */
 }
 
 psa_status_t psa_close_key( psa_key_handle_t handle )
diff --git a/tests/suites/test_suite_psa_crypto_slot_management.data b/tests/suites/test_suite_psa_crypto_slot_management.data
index 68b196d32..147773416 100644
--- a/tests/suites/test_suite_psa_crypto_slot_management.data
+++ b/tests/suites/test_suite_psa_crypto_slot_management.data
@@ -160,7 +160,7 @@ depends_on:MBEDTLS_PSA_CRYPTO_STORAGE_C
 create_fail:PSA_KEY_LIFETIME_PERSISTENT:PSA_KEY_ID_USER_MAX + 1:PSA_ERROR_INVALID_ARGUMENT
 
 Open not supported
-depends_on:!MBEDTLS_PSA_CRYPTO_STORAGE_C
+depends_on:!MBEDTLS_PSA_CRYPTO_STORAGE_C:!MBEDTLS_PSA_CRYPTO_BUILTIN_KEYS
 open_fail:1:PSA_ERROR_NOT_SUPPORTED
 
 Create not supported