diff --git a/src/dynarmic/backend/x64/emit_x64_crc32.cpp b/src/dynarmic/backend/x64/emit_x64_crc32.cpp
index 6ad4c489..842a8612 100644
--- a/src/dynarmic/backend/x64/emit_x64_crc32.cpp
+++ b/src/dynarmic/backend/x64/emit_x64_crc32.cpp
@@ -22,7 +22,13 @@ static void EmitCRC32Castagnoli(BlockOfCode& code, EmitContext& ctx, IR::Inst* i
     if (code.HasHostFeature(HostFeature::SSE42)) {
         const Xbyak::Reg32 crc = ctx.reg_alloc.UseScratchGpr(args[0]).cvt32();
         const Xbyak::Reg value = ctx.reg_alloc.UseGpr(args[1]).changeBit(data_size);
-        code.crc32(crc, value);
+
+        if (data_size != 64) {
+            code.crc32(crc, value);
+        } else {
+            code.crc32(crc.cvt64(), value);
+        }
+
         ctx.reg_alloc.DefineValue(inst, crc);
         return;
     }