diff --git a/pkgs/applications/misc/polychromatic/default.nix b/pkgs/applications/misc/polychromatic/default.nix
new file mode 100644
index 000000000000..f27902a8aac7
--- /dev/null
+++ b/pkgs/applications/misc/polychromatic/default.nix
@@ -0,0 +1,108 @@
+{ lib
+, fetchFromGitHub
+, bash
+, cairo
+, glib
+, qt5
+, hicolor-icon-theme
+, gdk-pixbuf
+, imagemagick
+, desktop-file-utils
+, ninja
+, meson
+, sassc
+, ibus
+, usbutils
+, libxcb
+, python3Packages
+, gobject-introspection
+, gtk3
+, wrapGAppsHook
+, libappindicator-gtk3
+}:
+
+python3Packages.buildPythonApplication rec {
+  name = "polychromatic";
+  version = "0.7.3";
+
+  format = "other";
+
+  src = fetchFromGitHub {
+    owner = "polychromatic";
+    repo = "polychromatic";
+    rev = "v${version}";
+    sha256 = "sha256-H++kQ3Fxw56avEsSE1ctu5p0s50s0eQ+jL5zXS3AA94=";
+  };
+
+  postPatch = ''
+    patchShebangs scripts
+
+    substituteInPlace scripts/build-styles.sh \
+      --replace '$(which sassc 2>/dev/null)' '${sassc}/bin/sassc' \
+      --replace '$(which sass 2>/dev/null)' '${sassc}/bin/sass'
+
+    substituteInPlace pylib/common.py --replace "/usr/share/polychromatic" "$out/share/polychromatic"
+  '';
+
+  preConfigure = ''
+    scripts/build-styles.sh
+  '';
+
+  buildInputs = [
+    cairo
+    hicolor-icon-theme
+  ];
+
+  pythonPath = with python3Packages; [
+    openrazer
+    pyqt5
+    pyqtwebengine
+  ];
+
+  propagatedBuildInputs = with python3Packages; [
+    libxcb
+    colour
+    colorama
+    setproctitle
+    openrazer
+    openrazer-daemon
+    requests
+    ibus
+    usbutils
+    pyqt5
+    libappindicator-gtk3
+  ];
+
+  nativeBuildInputs = with python3Packages; [
+    pyqt5
+    desktop-file-utils
+    qt5.wrapQtAppsHook
+    wrapGAppsHook
+    ninja
+    meson
+    sassc
+  ];
+
+  propagatedNativeBuildInputs = [
+    gobject-introspection
+    gtk3
+    gdk-pixbuf
+    imagemagick
+  ];
+
+  makeWrapperArgs = [
+    "\${qtWrapperArgs[@]}"
+  ];
+
+  meta = with lib; {
+    homepage = "https://polychromatic.app/";
+    description = "Graphical front-end and tray applet for configuring Razer peripherals on GNU/Linux.";
+    longDescription = ''
+      Polychromatic is a frontend for OpenRazer that enables Razer devices
+      to control lighting effects and more on GNU/Linux.
+    '';
+    license = licenses.gpl3;
+    platforms = platforms.linux;
+    maintainers = with maintainers; [ evanjs ];
+  };
+}
diff --git a/pkgs/top-level/all-packages.nix b/pkgs/top-level/all-packages.nix
index ea1d91c782f9..168367a8a598 100644
--- a/pkgs/top-level/all-packages.nix
+++ b/pkgs/top-level/all-packages.nix
@@ -24731,6 +24731,8 @@ with pkgs;
 
   poly = callPackage ../data/fonts/poly { };
 
+  polychromatic = libsForQt5.callPackage ../applications/misc/polychromatic { };
+
   polytopes_db = callPackage ../data/misc/polytopes_db { };
 
   pop-gtk-theme = callPackage ../data/themes/pop-gtk { };