diff --git a/nixos/doc/manual/from_md/release-notes/rl-2111.section.xml b/nixos/doc/manual/from_md/release-notes/rl-2111.section.xml
index 3c60226b224d..75513ed7e733 100644
--- a/nixos/doc/manual/from_md/release-notes/rl-2111.section.xml
+++ b/nixos/doc/manual/from_md/release-notes/rl-2111.section.xml
@@ -1240,6 +1240,19 @@ Superuser created successfully.
           directories, thus increasing the purity of the build.
         </para>
       </listitem>
+      <listitem>
+        <para>
+          Three new options,
+          <link linkend="opt-xdg.mime.addedAssociations">xdg.mime.addedAssociations</link>,
+          <link linkend="opt-xdg.mime.defaultApplications">xdg.mime.defaultApplications</link>,
+          and
+          <link linkend="opt-xdg.mime.removedAssociations">xdg.mime.removedAssociations</link>
+          have been added to the
+          <link linkend="opt-xdg.mime.enable">xdg.mime</link> module to
+          allow the configuration of
+          <literal>/etc/xdg/mimeapps.list</literal>.
+        </para>
+      </listitem>
     </itemizedlist>
   </section>
 </section>
diff --git a/nixos/doc/manual/release-notes/rl-2111.section.md b/nixos/doc/manual/release-notes/rl-2111.section.md
index 256c15fb4988..a55fbbe2afdb 100644
--- a/nixos/doc/manual/release-notes/rl-2111.section.md
+++ b/nixos/doc/manual/release-notes/rl-2111.section.md
@@ -367,3 +367,5 @@ To be able to access the web UI this port needs to be opened in the firewall.
 
 - `lua` and `luajit` interpreters have been patched to avoid looking into /usr/lib
   directories, thus increasing the purity of the build.
+
+- Three new options, [xdg.mime.addedAssociations](#opt-xdg.mime.addedAssociations), [xdg.mime.defaultApplications](#opt-xdg.mime.defaultApplications), and [xdg.mime.removedAssociations](#opt-xdg.mime.removedAssociations) have been added to the [xdg.mime](#opt-xdg.mime.enable) module to allow the configuration of `/etc/xdg/mimeapps.list`.
diff --git a/nixos/modules/config/xdg/mime.nix b/nixos/modules/config/xdg/mime.nix
index 4cdb3f30994b..9b6dd4cab5f5 100644
--- a/nixos/modules/config/xdg/mime.nix
+++ b/nixos/modules/config/xdg/mime.nix
@@ -1,9 +1,17 @@
 { config, lib, pkgs, ... }:
 
 with lib;
+
+let
+  cfg = config.xdg.mime;
+  associationOptions = with types; attrsOf (
+    coercedTo (either (listOf str) str) (x: concatStringsSep ";" (toList x)) str
+  );
+in
+
 {
   meta = {
-    maintainers = teams.freedesktop.members;
+    maintainers = teams.freedesktop.members ++ (with maintainers; [ figsoda ]);
   };
 
   options = {
@@ -16,9 +24,63 @@ with lib;
         <link xlink:href="https://specifications.freedesktop.org/mime-apps-spec/mime-apps-spec-latest.html">XDG MIME Applications specification</link>.
       '';
     };
+
+    xdg.mime.addedAssociations = mkOption {
+      type = associationOptions;
+      default = {};
+      example = {
+        "application/pdf" = "firefox.desktop";
+        "text/xml" = [ "nvim.desktop" "codium.desktop" ];
+      };
+      description = ''
+        Adds associations between mimetypes and applications. See the
+        <link xlink:href="https://specifications.freedesktop.org/mime-apps-spec/mime-apps-spec-latest.html#associations">
+        specifications</link> for more information.
+      '';
+    };
+
+    xdg.mime.defaultApplications = mkOption {
+      type = associationOptions;
+      default = {};
+      example = {
+        "application/pdf" = "firefox.desktop";
+        "image/png" = [ "sxiv.desktop" "gimp.desktop" ];
+      };
+      description = ''
+        Sets the default applications for given mimetypes. See the
+        <link xlink:href="https://specifications.freedesktop.org/mime-apps-spec/mime-apps-spec-latest.html#default">
+        specifications</link> for more information.
+      '';
+    };
+
+    xdg.mime.removedAssociations = mkOption {
+      type = associationOptions;
+      default = {};
+      example = {
+        "audio/mp3" = [ "mpv.desktop" "umpv.desktop" ];
+        "inode/directory" = "codium.desktop";
+      };
+      description = ''
+        Removes associations between mimetypes and applications. See the
+        <link xlink:href="https://specifications.freedesktop.org/mime-apps-spec/mime-apps-spec-latest.html#associations">
+        specifications</link> for more information.
+      '';
+    };
   };
 
-  config = mkIf config.xdg.mime.enable {
+  config = mkIf cfg.enable {
+    environment.etc."xdg/mimeapps.list" = mkIf (
+      cfg.addedAssociations != {}
+      || cfg.defaultApplications != {}
+      || cfg.removedAssociations != {}
+    ) {
+      text = generators.toINI { } {
+        "Added Associations" = cfg.addedAssociations;
+        "Default Applications" = cfg.defaultApplications;
+        "Removed Associations" = cfg.removedAssociations;
+      };
+    };
+
     environment.pathsToLink = [ "/share/mime" ];
 
     environment.systemPackages = [