diff --git a/pkgs/development/python-modules/pygame-gui/default.nix b/pkgs/development/python-modules/pygame-gui/default.nix
new file mode 100644
index 000000000000..58f65b6d0f41
--- /dev/null
+++ b/pkgs/development/python-modules/pygame-gui/default.nix
@@ -0,0 +1,53 @@
+{ lib
+, pkgs
+, buildPythonPackage
+, fetchFromGitHub
+, pygame
+, pytestCheckHook
+}:
+
+buildPythonPackage rec {
+  pname = "pygame-gui";
+  version = "0.5.7";
+
+  src = fetchFromGitHub {
+    owner = "MyreMylar";
+    repo = "pygame_gui";
+    rev = "v_${lib.replaceStrings ["."] [""] version}";
+    sha256 = "4P2PT8/7oA5Q7H4+pm7BOET7w05pQYQltXVV3+YVrVE=";
+  };
+
+  propagatedBuildInputs = [ pygame ];
+
+  postPatch = ''
+    substituteInPlace pygame_gui/core/utility.py \
+      --replace "xsel" "${pkgs.xsel}/bin/xsel"
+  '';
+
+  checkInputs = [ pytestCheckHook ];
+
+  preCheck = ''
+    export HOME=$TMPDIR
+    export SDL_VIDEODRIVER=dummy
+  '';
+
+  disabledTests = [
+    # Clipboard doesn't exist in test environment
+    "test_process_event_text_ctrl_c"
+    "test_process_event_text_ctrl_v"
+    "test_process_event_text_ctrl_v_nothing"
+    "test_process_event_ctrl_v_over_limit"
+    "test_process_event_ctrl_v_at_limit"
+    "test_process_event_ctrl_v_over_limit_select_range"
+    "test_process_event_text_ctrl_v_select_range"
+    "test_process_event_text_ctrl_a"
+    "test_process_event_text_ctrl_x"
+  ];
+
+  meta = with lib; {
+    description = "A GUI system for pygame";
+    homepage = "https://github.com/MyreMylar/pygame_gui";
+    license = with licenses; [ mit ];
+    maintainers = with maintainers; [ angustrau ];
+  };
+}
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 172fdc4b6681..fd469440e8b6 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -6007,6 +6007,8 @@ in {
 
   pygame_sdl2 = callPackage ../development/python-modules/pygame_sdl2 { };
 
+  pygame-gui = callPackage ../development/python-modules/pygame-gui { };
+
   pygatt = callPackage ../development/python-modules/pygatt { };
 
   pygbm = callPackage ../development/python-modules/pygbm { };