diff --git a/pkgs/development/python-modules/filemagic/default.nix b/pkgs/development/python-modules/filemagic/default.nix
deleted file mode 100644
index 96ee0a95b283..000000000000
--- a/pkgs/development/python-modules/filemagic/default.nix
+++ /dev/null
@@ -1,30 +0,0 @@
-{ stdenv, lib, buildPythonPackage, fetchFromGitHub, file
-, isPy3k, mock, unittest2 }:
-
-buildPythonPackage {
-  pname = "filemagic";
-  version = "1.6";
-  disabled = !isPy3k; # asserts on ResourceWarning
-
-  # Don't use the PyPI source because it's missing files required for testing
-  src = fetchFromGitHub {
-    owner = "aliles";
-    repo = "filemagic";
-    rev = "138649062f769fb10c256e454a3e94ecfbf3017b";
-    sha256 = "1jxf928jjl2v6zv8kdnfqvywdwql1zqkm1v5xn1d5w0qjcg38d4n";
-  };
-
-  postPatch = ''
-    substituteInPlace magic/api.py --replace "ctypes.util.find_library('magic')" \
-      "'${file}/lib/libmagic${stdenv.hostPlatform.extensions.sharedLibrary}'"
-  '';
-
-  checkInputs = [ mock ] ++ lib.optionals (!isPy3k) [ unittest2 ];
-
-  meta = with lib; {
-    description = "File type identification using libmagic";
-    homepage = "https://github.com/aliles/filemagic";
-    license = licenses.asl20;
-    maintainers = with maintainers; [ erikarvstedt ];
-  };
-}
diff --git a/pkgs/development/tools/poetry2nix/poetry2nix/overrides/build-systems.json b/pkgs/development/tools/poetry2nix/poetry2nix/overrides/build-systems.json
index e2e674d967bd..e5d5c946a403 100644
--- a/pkgs/development/tools/poetry2nix/poetry2nix/overrides/build-systems.json
+++ b/pkgs/development/tools/poetry2nix/poetry2nix/overrides/build-systems.json
@@ -4816,9 +4816,6 @@
     "setuptools",
     "setuptools-scm"
   ],
-  "filemagic": [
-    "setuptools"
-  ],
   "filetype": [
     "setuptools"
   ],
diff --git a/pkgs/top-level/python-aliases.nix b/pkgs/top-level/python-aliases.nix
index eb85a22c71e2..fd1f7cb50bf9 100644
--- a/pkgs/top-level/python-aliases.nix
+++ b/pkgs/top-level/python-aliases.nix
@@ -77,6 +77,7 @@ mapAliases ({
   face_recognition_models = face-recognition-models; # added 2022-10-15
   fake_factory = throw "fake_factory has been removed because it is unused and deprecated by upstream since 2016."; # added 2022-05-30
   faulthandler = throw "faulthandler is built into ${python.executable}"; # added 2021-07-12
+  filemagic = throw "inactive since 2014, so use python-magic instead"; # added 2022-11-19
   flask_login = flask-login; # added 2022-10-17
   flask_sqlalchemy = flask-sqlalchemy; # added 2022-07-20
   flask_testing = flask-testing; # added 2022-04-25
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 431d9a46cba7..18ebf402c3c6 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -3228,8 +3228,6 @@ self: super: with self; {
 
   filelock = callPackage ../development/python-modules/filelock { };
 
-  filemagic = callPackage ../development/python-modules/filemagic { };
-
   filetype = callPackage ../development/python-modules/filetype { };
 
   filterpy = callPackage ../development/python-modules/filterpy { };