diff --git a/pkgs/development/python-modules/symengine/default.nix b/pkgs/development/python-modules/symengine/default.nix
index 38ceda098209..599b2e74566b 100644
--- a/pkgs/development/python-modules/symengine/default.nix
+++ b/pkgs/development/python-modules/symengine/default.nix
@@ -1,6 +1,5 @@
 { lib
 , buildPythonPackage
-, fetchpatch
 , fetchFromGitHub
 , cython
 , cmake
@@ -22,14 +21,6 @@ buildPythonPackage rec {
     hash = "sha256-03lHip0iExfptrUe5ObA6xXrsfS4QJPrh1Z0v7q2lDI=";
   };
 
-  patches = [
-    (fetchpatch {
-      # setuptools 61 compat
-      url = "https://github.com/symengine/symengine.py/commit/987e665e71cf92d1b021d7d573a1b9733408eecf.patch";
-      hash = "sha256-2QbNdw/lKYRIRpOU5BiwF2kK+5Lh2j/Q82MKUIvl0+c=";
-    })
-  ];
-
   postPatch = ''
     substituteInPlace setup.py \
       --replace "\"cmake\"" "\"${cmake}/bin/cmake\"" \