diff --git a/doc/languages-frameworks/python.section.md b/doc/languages-frameworks/python.section.md
index dc10483ce694..7bee48773c29 100644
--- a/doc/languages-frameworks/python.section.md
+++ b/doc/languages-frameworks/python.section.md
@@ -640,8 +640,8 @@ and in this case the `python38` interpreter is automatically used.
 
 ### Interpreters
 
-Versions 2.7, 3.5, 3.6, 3.7 and 3.8 of the CPython interpreter are available as
-respectively `python27`, `python35`, `python36`, `python37` and `python38`. The
+Versions 2.7, 3.6, 3.7 and 3.8 of the CPython interpreter are available as
+respectively `python27`, `python36`, `python37` and `python38`. The
 aliases `python2` and `python3` correspond to respectively `python27` and
 `python38`. The default interpreter, `python`, maps to `python2`. The PyPy
 interpreters compatible with Python 2.7 and 3 are available as `pypy27` and
@@ -689,15 +689,16 @@ attribute set is created for each available Python interpreter. The available
 sets are
 
 * `pkgs.python27Packages`
-* `pkgs.python35Packages`
 * `pkgs.python36Packages`
 * `pkgs.python37Packages`
+* `pkgs.python38Packages`
+* `pkgs.python39Packages`
 * `pkgs.pypyPackages`
 
 and the aliases
 
 * `pkgs.python2Packages` pointing to `pkgs.python27Packages`
-* `pkgs.python3Packages` pointing to `pkgs.python37Packages`
+* `pkgs.python3Packages` pointing to `pkgs.python38Packages`
 * `pkgs.pythonPackages` pointing to `pkgs.python2Packages`
 
 #### `buildPythonPackage` function
diff --git a/pkgs/development/interpreters/python/default.nix b/pkgs/development/interpreters/python/default.nix
index c9c313b437ae..76963587c20d 100644
--- a/pkgs/development/interpreters/python/default.nix
+++ b/pkgs/development/interpreters/python/default.nix
@@ -63,19 +63,6 @@ in {
     inherit passthruFun;
   };
 
-  python35 = callPackage ./cpython {
-    self = python35;
-    sourceVersion = {
-      major = "3";
-      minor = "5";
-      patch = "9";
-      suffix = "";
-    };
-    sha256 = "0jdh9pvx6m6lfz2liwvvhn7vks7qrysqgwn517fkpxb77b33fjn2";
-    inherit (darwin) configd;
-    inherit passthruFun;
-  };
-
   python36 = callPackage ./cpython {
     self = python36;
     sourceVersion = {
diff --git a/pkgs/development/python-modules/ipython/7.9.nix b/pkgs/development/python-modules/ipython/7.9.nix
deleted file mode 100644
index 9953868df5f3..000000000000
--- a/pkgs/development/python-modules/ipython/7.9.nix
+++ /dev/null
@@ -1,69 +0,0 @@
-{ lib
-, stdenv
-, buildPythonPackage
-, fetchPypi
-, pythonOlder
-# Build dependencies
-, glibcLocales
-# Test dependencies
-, nose
-, pygments
-# Runtime dependencies
-, jedi
-, decorator
-, pickleshare
-, traitlets
-, prompt_toolkit
-, pexpect
-, appnope
-, backcall
-, fetchpatch
-}:
-
-buildPythonPackage rec {
-  pname = "ipython";
-  version = "7.9.0";
-
-  src = fetchPypi {
-    inherit pname version;
-    sha256 = "103jkw18z7fnwdal1mdbijjxi1fndzn31g887lmj7ddpf2r07lyz";
-  };
-
-  prePatch = lib.optionalString stdenv.isDarwin ''
-    substituteInPlace setup.py --replace "'gnureadline'" " "
-  '';
-
-  buildInputs = [ glibcLocales ];
-
-  checkInputs = [ nose pygments ];
-
-  propagatedBuildInputs = [
-    jedi
-    decorator
-    pickleshare
-    traitlets
-    prompt_toolkit
-    pygments
-    pexpect
-    backcall
-  ] ++ lib.optionals stdenv.isDarwin [appnope];
-
-  LC_ALL="en_US.UTF-8";
-
-  doCheck = false; # Circular dependency with ipykernel
-
-  checkPhase = ''
-    nosetests
-  '';
-
-  pythonImportsCheck = [
-    "IPython"
-  ];
-
-  meta = with lib; {
-    description = "IPython: Productive Interactive Computing";
-    homepage = "http://ipython.org/";
-    license = licenses.bsd3;
-    maintainers = with maintainers; [ bjornfor ];
-  };
-}
diff --git a/pkgs/top-level/all-packages.nix b/pkgs/top-level/all-packages.nix
index 0964ed81cb96..53e91e27ab17 100644
--- a/pkgs/top-level/all-packages.nix
+++ b/pkgs/top-level/all-packages.nix
@@ -9896,7 +9896,6 @@ in
   python2Full = python2.override{x11Support=true;};
   python27Full = python27.override{x11Support=true;};
   python3Full = python3.override{x11Support=true;};
-  python35Full = python35.override{x11Support=true;};
   python36Full = python36.override{x11Support=true;};
   python37Full = python37.override{x11Support=true;};
   python38Full = python38.override{x11Support=true;};
@@ -9908,11 +9907,10 @@ in
   python3Packages = python3.pkgs;
 
   pythonInterpreters = callPackage ./../development/interpreters/python {};
-  inherit (pythonInterpreters) python27 python35 python36 python37 python38 python39 python3Minimal pypy27 pypy36;
+  inherit (pythonInterpreters) python27 python36 python37 python38 python39 python3Minimal pypy27 pypy36;
 
   # Python package sets.
   python27Packages = lib.hiPrioSet (recurseIntoAttrs python27.pkgs);
-  python35Packages = python35.pkgs;
   python36Packages = python36.pkgs;
   python37Packages = recurseIntoAttrs python37.pkgs;
   python38Packages = recurseIntoAttrs python38.pkgs;
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 598b55d7c92a..17bb020c8a27 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -4424,8 +4424,6 @@ in {
 
   ipython = if isPy27 then
       callPackage ../development/python-modules/ipython/5.nix { }
-    else if isPy35 then
-      callPackage ../development/python-modules/ipython/7.9.nix { }
     else
       callPackage ../development/python-modules/ipython { };
 
diff --git a/pkgs/top-level/static.nix b/pkgs/top-level/static.nix
index 2d7f0883ca25..ca64c4d975cb 100644
--- a/pkgs/top-level/static.nix
+++ b/pkgs/top-level/static.nix
@@ -269,7 +269,6 @@ in {
   ) super.ocaml-ng;
 
   python27 = super.python27.override { static = true; };
-  python35 = super.python35.override { static = true; };
   python36 = super.python36.override { static = true; };
   python37 = super.python37.override { static = true; };
   python38 = super.python38.override { static = true; };