diff --git a/pkgs/applications/audio/muse/default.nix b/pkgs/applications/audio/muse/default.nix
index 01940bfc4f32..fb80c10f046f 100644
--- a/pkgs/applications/audio/muse/default.nix
+++ b/pkgs/applications/audio/muse/default.nix
@@ -1,33 +1,68 @@
-{ lib, stdenv, fetchFromGitHub, cmake, pkg-config, qttools, wrapQtAppsHook
-, alsa-lib, dssi, fluidsynth, ladspaH, lash, libinstpatch, libjack2, liblo
-, libsamplerate, libsndfile, lilv, lrdf, lv2, qtsvg, rtaudio, rubberband, sord, serd
+{ lib
+, stdenv
+, fetchFromGitHub
+, cmake
+, pkg-config
+, qttools
+, wrapQtAppsHook
+, alsa-lib
+, dssi
+, fluidsynth
+, ladspaH
+, lash
+, libinstpatch
+, libjack2
+, liblo
+, libsamplerate
+, libsndfile
+, lilv
+, lrdf
+, lv2
+, qtsvg
+, rtaudio
+, rubberband
+, sord
+, serd
 }:
 
-stdenv.mkDerivation rec {
+stdenv.mkDerivation (finalAttrs: {
   pname = "muse-sequencer";
-  version = "3.1.1";
+  version = "4.1.0";
 
   src = fetchFromGitHub {
     owner = "muse-sequencer";
     repo = "muse";
-    rev = "muse_${builtins.replaceStrings ["."] ["_"] version}";
-    sha256 = "1rasp2v1ds2aw296lbf27rzw0l9fjl0cvbvw85d5ycvh6wkm301p";
+    rev = finalAttrs.version;
+    hash = "sha256-JPvoximDL4oKO8reXW7alMegwUyUTSAcdq3ueXeUMMY=";
   };
 
-  sourceRoot = "${src.name}/muse3";
-
-  patches = [ ./fix-parallel-building.patch ];
+  sourceRoot = "${finalAttrs.src.name}/src";
 
   nativeBuildInputs = [ cmake pkg-config qttools wrapQtAppsHook ];
 
   buildInputs = [
-    alsa-lib dssi fluidsynth ladspaH lash libinstpatch libjack2 liblo
-    libsamplerate libsndfile lilv lrdf lv2 qtsvg rtaudio rubberband sord
+    alsa-lib
+    dssi
+    fluidsynth
+    ladspaH
+    lash
+    libinstpatch
+    libjack2
+    liblo
+    libsamplerate
+    libsndfile
+    lilv
+    lrdf
+    lv2
+    qtsvg
+    rtaudio
+    rubberband
+    sord
   ];
 
   env.NIX_CFLAGS_COMPILE = toString [ "-I${lib.getDev serd}/include/serd-0" ];
 
-  meta = with lib; {
+  meta = {
     homepage = "https://muse-sequencer.github.io/";
     description = "MIDI/Audio sequencer with recording and editing capabilities";
     longDescription = ''
@@ -38,7 +73,9 @@ stdenv.mkDerivation rec {
       MusE aims to be a complete multitrack virtual studio for Linux,
       it is published under the GNU General Public License.
     '';
-    license = licenses.gpl2Plus;
-    maintainers = with maintainers; [ orivej ];
+    license = lib.licenses.gpl2Plus;
+    maintainers = with lib.maintainers; [ eclairevoyant orivej ];
+    platforms = lib.platforms.linux;
+    mainProgram = "muse4";
   };
-}
+})
diff --git a/pkgs/applications/audio/muse/fix-parallel-building.patch b/pkgs/applications/audio/muse/fix-parallel-building.patch
deleted file mode 100644
index a11970b7111a..000000000000
--- a/pkgs/applications/audio/muse/fix-parallel-building.patch
+++ /dev/null
@@ -1,93 +0,0 @@
-To confirm these dependencies, run in a fresh build tree:
-
-
-ninja muse/components/CMakeFiles/components.dir/confmport.o
-
-In file included from ../muse/components/confmport.cpp:48:
-../muse/mplugins/midifilterimpl.h:28:10: fatal error:
-ui_midifilter.h: No such file or directory
-
-
-ninja muse/waveedit/CMakeFiles/waveedit.dir/wavecanvas.o
-
-In file included from ../muse/waveedit/wavecanvas.cpp:72:
-../muse/components/copy_on_write.h:26:10: fatal error:
-ui_copy_on_write_base.h: No such file or directory
-
-
-ninja muse/instruments/CMakeFiles/instruments.dir/editinstrument.o
-
-In file included from ../muse/instruments/editinstrument.cpp:58:
-../muse/components/editevent.h:26:10: fatal error:
-ui_editnotedialogbase.h: No such file or directory
-
-
-ninja muse/liste/CMakeFiles/liste.dir/listedit.o
-
-In file included from ../muse/liste/listedit.cpp:37:
-../muse/components/editevent.h:26:10: fatal error:
-ui_editnotedialogbase.h: No such file or directory
-
-
-ninja muse/mixer/CMakeFiles/mixer.dir/rack.o
-
-In file included from ../muse/mixer/rack.cpp:49:
-../muse/components/plugindialog.h:4:10: fatal error:
-ui_plugindialogbase.h: No such file or directory
-
-
-ninja muse/midiedit/CMakeFiles/midiedit.dir/drumedit.o
-
-In file included from /build/source/muse3/muse/midiedit/drumedit.cpp:64:
-/build/source/muse3/muse/components/filedialog.h:29:10: fatal error:
-ui_fdialogbuttons.h: No such file or directory
-
-
---- a/muse/components/CMakeLists.txt
-+++ b/muse/components/CMakeLists.txt
-@@ -343,4 +343,5 @@ set_target_properties( components
- target_link_libraries ( components
-       ${QT_LIBRARIES}
-+      mplugins
-       widgets
-       xml_module
---- a/muse/waveedit/CMakeLists.txt
-+++ b/muse/waveedit/CMakeLists.txt
-@@ -79,4 +79,5 @@ set_target_properties( waveedit
- target_link_libraries( waveedit
-       ${QT_LIBRARIES}
-+      components
-       widgets
-       )
---- a/muse/instruments/CMakeLists.txt
-+++ b/muse/instruments/CMakeLists.txt
-@@ -78,4 +78,5 @@ set_target_properties( instruments
- target_link_libraries ( instruments
-       ${QT_LIBRARIES}
-+      components
-       icons
-       widgets
---- a/muse/liste/CMakeLists.txt
-+++ b/muse/liste/CMakeLists.txt
-@@ -65,4 +65,5 @@ set_target_properties( liste
- target_link_libraries ( liste
-       ${QT_LIBRARIES}
-+      components
-       awl
-       widgets
---- a/muse/mixer/CMakeLists.txt
-+++ b/muse/mixer/CMakeLists.txt
-@@ -87,4 +87,5 @@ set_target_properties ( mixer
- target_link_libraries ( mixer
-       ${QT_LIBRARIES}
-+      components
-       widgets
-       )
---- a/muse/midiedit/CMakeLists.txt
-+++ b/muse/midiedit/CMakeLists.txt
-@@ -93,4 +93,5 @@ set_target_properties( midiedit
- target_link_libraries ( midiedit
-       ${QT_LIBRARIES}
-+      components
-       al
-       ctrl