diff --git a/pkgs/development/compilers/llvm/12/compiler-rt/default.nix b/pkgs/development/compilers/llvm/12/compiler-rt/default.nix
index 13c611ca8cc6..4b2907ed3078 100644
--- a/pkgs/development/compilers/llvm/12/compiler-rt/default.nix
+++ b/pkgs/development/compilers/llvm/12/compiler-rt/default.nix
@@ -30,6 +30,7 @@ stdenv.mkDerivation {
     "-DCOMPILER_RT_BUILD_XRAY=OFF"
     "-DCOMPILER_RT_BUILD_LIBFUZZER=OFF"
     "-DCOMPILER_RT_BUILD_PROFILE=OFF"
+    "-DCOMPILER_RT_BUILD_MEMPROF=OFF"
   ] ++ lib.optionals ((useLLVM || bareMetal) && !haveLibc) [
     "-DCMAKE_C_COMPILER_WORKS=ON"
     "-DCMAKE_CXX_COMPILER_WORKS=ON"
diff --git a/pkgs/development/compilers/llvm/13/compiler-rt/default.nix b/pkgs/development/compilers/llvm/13/compiler-rt/default.nix
index e30db5fcd954..10b89b91b96f 100644
--- a/pkgs/development/compilers/llvm/13/compiler-rt/default.nix
+++ b/pkgs/development/compilers/llvm/13/compiler-rt/default.nix
@@ -33,6 +33,8 @@ stdenv.mkDerivation {
     "-DCOMPILER_RT_BUILD_SANITIZERS=OFF"
     "-DCOMPILER_RT_BUILD_XRAY=OFF"
     "-DCOMPILER_RT_BUILD_PROFILE=OFF"
+    "-DCOMPILER_RT_BUILD_MEMPROF=OFF"
+    "-DCOMPILER_RT_BUILD_ORC=OFF" # may be possible to build with musl if necessary
   ] ++ lib.optionals ((useLLVM || bareMetal) && !haveLibc) [
     "-DCMAKE_C_COMPILER_WORKS=ON"
     "-DCMAKE_CXX_COMPILER_WORKS=ON"
diff --git a/pkgs/development/compilers/llvm/git/compiler-rt/default.nix b/pkgs/development/compilers/llvm/git/compiler-rt/default.nix
index 5874a91e03c8..019148039d17 100644
--- a/pkgs/development/compilers/llvm/git/compiler-rt/default.nix
+++ b/pkgs/development/compilers/llvm/git/compiler-rt/default.nix
@@ -32,6 +32,8 @@ stdenv.mkDerivation {
     "-DCOMPILER_RT_BUILD_XRAY=OFF"
     "-DCOMPILER_RT_BUILD_LIBFUZZER=OFF"
     "-DCOMPILER_RT_BUILD_PROFILE=OFF"
+    "-DCOMPILER_RT_BUILD_MEMPROF=OFF"
+    "-DCOMPILER_RT_BUILD_ORC=OFF" # may be possible to build with musl if necessary
   ] ++ lib.optionals ((useLLVM || bareMetal) && !haveLibc) [
     "-DCMAKE_C_COMPILER_WORKS=ON"
     "-DCMAKE_CXX_COMPILER_WORKS=ON"