diff --git a/pkgs/development/python-modules/libnacl/default.nix b/pkgs/development/python-modules/libnacl/default.nix
index f8cb85ab4182..7ced26888b80 100644
--- a/pkgs/development/python-modules/libnacl/default.nix
+++ b/pkgs/development/python-modules/libnacl/default.nix
@@ -2,6 +2,7 @@
 , stdenv
 , buildPythonPackage
 , fetchFromGitHub
+, fetchpatch
 , libsodium
 , pytestCheckHook
 }:
@@ -17,6 +18,15 @@ buildPythonPackage rec {
     sha256 = "sha256-nttR9PQimhqd2pByJ5IJzJ4RmSI4y7lcX7a7jcK+vqc=";
   };
 
+  patches = [
+    # Fixes build on 32-bit platforms
+    (fetchpatch {
+      name = "fix-crypto_kdf_derive_from_key-32bit.patch";
+      url = "https://github.com/saltstack/libnacl/commit/e8a1f95ee1d4d0806fb6aee793dcf308b05d485d.patch";
+      sha256 = "sha256-z6TAVNfPcuWZ/hRgk6Aa8I1IGzne7/NYnUOOQ3TjGVU=";
+    })
+  ];
+
   buildInputs = [ libsodium ];
 
   postPatch =